John Currin made a good point about making art when your attitude toward it (and life) changes. After meeting his (now) wife and artist Rachel Feinstein, his outlook became much more positive:
"I came to the conclusion that there is no misery in art. All art is about saying yes, and all art is about its own making."
Photograph: ELINOR CARUCCI
"The New Yorker", Jan. 28, 2008, pp. 64.